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28 results for Melillo,+Giovanni

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ArticlesPeer ReviewedFull Text
Targeting hypoxia cell signaling for cancer therapy
Author / Creator:Melillo, Giovanni
Publisher:Netherlands: Springer Nature B.V
Journal title:Cancer and metastasis reviews, 2007-06, Vol.26 (2), p.341-352
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Development of HIF‐1 inhibitors for cancer therapy
Author / Creator:Onnis, Barbara ; Rapisarda, Annamaria ; Melillo, Giovanni
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of cellular and molecular medicine, 2009-09, Vol.13 (9a), p.2780-2786
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Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells
Author / Creator:Onnis, Barbara ; Fer, Nicole ; Rapisarda, Annamaria ; Perez, Victor S. ; Melillo, Giovanni
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-04, Vol.123 (4), p.1615-1629
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Hypoxia Potentiates Glioma-Mediated Immunosuppression
Author / Creator:Wei, Jun ; Wu, Adam ; Kong, Ling-Yuan ; Wang, Yongtao ; Fuller, Gregory ; Fokt, Isabella ; Melillo, Giovanni ; Priebe, Waldemar ; Heimberger, Amy B.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-01, Vol.6 (1), p.e16195-e16195
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SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
Author / Creator:Pai, Sara I. ; Cohen, Ezra E. W. ; Lin, Derrick ; Fountzilas, George ; Kim, Edward S. ; Mehlhorn, Holger ; Baste, Neus ; Clayburgh, Daniel ; Lipworth, Loren ; Resteghini, Carlo ; Shara, Nawar ; Fujii, Takashi ; Zhang, Jun ; Stokes, Michael ; Wang, Huifen ; Twumasi-Ankrah, Philip ; Wildsmith, Sophie ; Khaliq, Asud ; Melillo, Giovanni ; Shire, Norah
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2019-12, Vol.17 (1), p.429-429, Article 429
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HIF factors cooperate with PML‐RARα to promote acute promyelocytic leukemia progression and relapse
Author / Creator:Coltella, Nadia ; Percio, Stefano ; Valsecchi, Roberta ; Cuttano, Roberto ; Guarnerio, Jlenia ; Ponzoni, Maurilio ; Pandolfi, Pier Paolo ; Melillo, Giovanni ; Pattini, Linda ; Bernardi, Rosa
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2014-05, Vol.6 (5), p.640-650
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Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia
Author / Creator:Rapisarda, Annamaria ; Melillo, Giovanni
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2012-07, Vol.9 (7), p.378-390
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Accumulation of hypoxia-inducible factor-1α is limited by transcription-dependent depletion
Author / Creator:Demidenko, Zoya N ; Rapisarda, AnnaMaria ; Garayoa, Mercedes ; Giannakakou, Paraskevi ; Melillo, Giovanni ; Blagosklonny, Mikhail V
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2005-07, Vol.24 (30), p.4829-4838
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Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC
Author / Creator:Antonia, Scott J ; Villegas, Augusto ; Daniel, Davey ; Vicente, David ; Murakami, Shuji ; Hui, Rina ; Kurata, Takayasu ; Chiappori, Alberto ; Lee, Ki H ; de Wit, Maike ; Cho, Byoung C ; Bourhaba, Maryam ; Quantin, Xavier ; Tokito, Takaaki ; Mekhail, Tarek ; Planchard, David ; Kim, Young-Chul ; Karapetis, Christos S ; Hiret, Sandrine ; Ostoros, Gyula ; Kubota, Kaoru ; Gray, Jhanelle E ; Paz-Ares, Luis ; de Castro Carpeño, Javier ; Faivre-Finn, Corinne ; Reck, Martin ; Vansteenkiste, Johan ; Spigel, David R ; Wadsworth, Catherine ; Melillo, Giovanni ; Taboada, Maria ; Dennis, Phillip A ; Özgüroğlu, Mustafa
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-12, Vol.379 (24), p.2342-2350
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ArticlesPeer ReviewedFull Text
Regulation of BRCA1 by protein degradation
Author / Creator:Blagosklonny, Mikhail V ; An, Won G ; Melillo, Giovanni ; Nguyen, Phuongmai ; Trepel, Jane B ; Neckers, Leonard M
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 1999-11, Vol.18 (47), p.6460-6468
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Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer
Author / Creator:Antonia, Scott J ; Villegas, Augusto ; Daniel, Davey ; Vicente, David ; Murakami, Shuji ; Hui, Rina ; Yokoi, Takashi ; Chiappori, Alberto ; Lee, Ki H ; de Wit, Maike ; Cho, Byoung C ; Bourhaba, Maryam ; Quantin, Xavier ; Tokito, Takaaki ; Mekhail, Tarek ; Planchard, David ; Kim, Young-Chul ; Karapetis, Christos S ; Hiret, Sandrine ; Ostoros, Gyula ; Kubota, Kaoru ; Gray, Jhanelle E ; Paz-Ares, Luis ; de Castro Carpeño, Javier ; Wadsworth, Catherine ; Melillo, Giovanni ; Jiang, Haiyi ; Huang, Yifan ; Dennis, Phillip A ; Özgüroğlu, Mustafa
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-11, Vol.377 (20), p.1919-1929
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Hypoxia: a double-edged sword of immunity
Author / Creator:Sica, Antonio ; Melillo, Giovanni ; Varesio, Luigi
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Journal of molecular medicine (Berlin, Germany), 2011-07, Vol.89 (7), p.657-665
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Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors
Author / Creator:Jeong, Woondong ; Rapisarda, Annamaria ; Park, Sook Ryun ; Kinders, Robert J. ; Chen, Alice ; Melillo, Giovanni ; Turkbey, Baris ; Steinberg, Seth M. ; Choyke, Peter ; Doroshow, James H. ; Kummar, Shivaani
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2014-02, Vol.73 (2), p.343-348
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Targeting hypoxia cell signaling for cancer therapy: Hypoxia and cancer
Author / Creator:MELILLO, Giovanni
Publisher:Dordrecht: Springer
Journal title:Cancer and metastasis reviews, 2007, Vol.26 (2), p.341-352
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Weekly EZN-2208 (PEGylated SN-38) in combination with bevacizumab in patients with refractory solid tumors
Author / Creator:Jeong, Woondong ; Park, Sook Ryun ; Rapisarda, Annamaria ; Fer, Nicole ; Kinders, Robert J. ; Chen, Alice ; Melillo, Giovanni ; Turkbey, Baris ; Steinberg, Seth M. ; Choyke, Peter ; Doroshow, James H. ; Kummar, Shivaani
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2014-04, Vol.32 (2), p.340-346
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A phase I and pharmacokinetic study of oral perifosine with different loading schedules in patients with refractory neoplasms
Author / Creator:Figg, William D. ; Monga, Manish ; Headlee, Donna ; Shah, Avni ; Chau, Cindy H. ; Peer, Cody ; Messman, Richard ; Elsayed, Yusri A. ; Murgo, Anthony J. ; Melillo, Giovanni ; Ryan, Qin C. ; Kalnitskiy, Mikhail ; Senderowicz, Adrian M. ; Hollingshead, Melinda ; Arbuck, Susan G. ; Sausville, Edward A.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2014-11, Vol.74 (5), p.955-967
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Phase II, randomized, open-label study of durvalumab : CONDOR
Author / Creator:Gilbert, Jill ; Le Tourneau, Christophe ; Mehanna, Hisham ; Fayette, Jerome ; Goswami, Trishna ; Emeribe, Ugochi ; Jarkowski, Anthony ; Melillo, Giovanni ; Siu, Lilian L
Publisher:BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2)
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phase I trial of UCN-01 and prednisone in patients with refractory solid tumors and lymphomas
Author / Creator:Kummar, Shivaani ; Gutierrez, Martin E ; Gardner, Erin R ; Figg, William D ; Melillo, Giovanni ; Dancey, Janet ; Sausville, Edward A ; Conley, Barbara A ; Murgo, Anthony J ; Doroshow, James H
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2010-01, Vol.65 (2), p.383-389
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Phase II, randomized, open-label study of durvalumab (MEDI4736) or tremelimumab monotherapy, or durvalumab + tremelimumab, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the...
Author / Creator:Gilbert, Jill ; Le Tourneau, Christophe ; Mehanna, Hisham ; Fayette, Jerome ; Goswami, Trishna ; Emeribe, Ugochi ; Jarkowski, Anthony ; Melillo, Giovanni ; Siu, Lilian L
Publisher:London: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2015-11, Vol.3 (S2), p.P152-P152, Article P152
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Phase III, randomized, open-label study of durvalumab (MEDI4736) monotherapy, or durvalumab + tremelimumab, versus standard of care (SoC), in recurrent or metastatic (R/M) squamous cell carcinoma of t...
Author / Creator:Ferris, Robert L ; Even, Caroline ; Haddad, Robert ; Tahara, Makoto ; Goswami, Trishna ; Franks, April ; Emeribe, Ugochi ; Jarkowski, Anthony ; Melillo, Giovanni ; Licitra, Lisa
Publisher:London: BioMed Central Ltd
Journal title:Journal for immunotherapy of cancer, 2015-11, Vol.3 (S2), p.P150-P150, Article P150
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Showing 1 to 20 of 28 results

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Targeting hypoxia cell signaling for cancer therapy

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Development of HIF‐1 inhibitors for cancer therapy

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Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells

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Hypoxia Potentiates Glioma-Mediated Immunosuppression

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SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck

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HIF factors cooperate with PML‐RARα to promote acute promyelocytic leukemia progression and relapse

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Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia

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Accumulation of hypoxia-inducible factor-1α is limited by transcription-dependent depletion

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Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC

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Regulation of BRCA1 by protein degradation

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Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer

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Hypoxia: a double-edged sword of immunity

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Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors

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Targeting hypoxia cell signaling for cancer therapy: Hypoxia and cancer

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Weekly EZN-2208 (PEGylated SN-38) in combination with bevacizumab in patients with refractory solid tumors

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A phase I and pharmacokinetic study of oral perifosine with different loading schedules in patients with refractory neoplasms

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Phase II, randomized, open-label study of durvalumab : CONDOR

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phase I trial of UCN-01 and prednisone in patients with refractory solid tumors and lymphomas

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Phase II, randomized, open-label study of durvalumab (MEDI4736) or tremelimumab monotherapy, or durvalumab + tremelimumab, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the...

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Phase III, randomized, open-label study of durvalumab (MEDI4736) monotherapy, or durvalumab + tremelimumab, versus standard of care (SoC), in recurrent or metastatic (R/M) squamous cell carcinoma of t...

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