The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and A[beta] generation in v...
The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and A[beta] generation in vivo
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New York: Springer Nature B.V
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English
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New York: Springer Nature B.V
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The cholesterol-synthesizing enzyme seladin-1, encoded by the Dhcr24 gene, is a flavin adenine dinucleotide-dependent oxidoreductase and regulates responses to oncogenic and oxidative stimuli. It has a role in neuroprotection and is downregulated in affected neurons in Alzheimer's disease (AD). Here we show that seladin-1-deficient mouse brains had...
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The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and A[beta] generation in vivo
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TN_cdi_proquest_miscellaneous_17480511
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17480511
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ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7600938
