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PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17494523

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

About this item

Full title

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2000-03, Vol.404 (6776), p.402-407

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Productive interaction of a T lymphocyte with an antigen-presenting cell results in the clustering of the T-cell antigen receptor (TCR) and the recruitment of a large signalling complex to the site of cell–cell contact
1
,
2
. Subsequent signal transduction resulting in cytokine gene expression requires the activation of one or more of...

Alternative Titles

Full title

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17494523

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17494523

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/35006090

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