Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BRE...
Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial
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Author / Creator
Long, Georgina V, Dr , Trefzer, Uwe, MD , Davies, Michael A, MD , Kefford, Richard F, Prof , Ascierto, Paolo A, MD , Chapman, Paul B, MD , Puzanov, Igor, MD , Hauschild, Axel, MD , Robert, Caroline, PhD , Algazi, Alain, MD , Mortier, Laurent, Prof , Tawbi, Hussein, PhD , Wilhelm, Tabea, MD , Zimmer, Lisa, MD , Switzky, Julie, MSN , Swann, Suzanne, PhD , Martin, Anne-Marie, PhD , Guckert, Mary, MSN , Goodman, Vicki, MD , Streit, Michael, MD , Kirkwood, John M, Prof and Schadendorf, Dirk, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Brain metastases are common in patients with metastatic melanoma and median overall survival from their diagnosis is typically 17–22 weeks. We assessed dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain. Methods We undertook a multicentre, open-label, phase 2 trial in 24 centres in six...
Alternative Titles
Full title
Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Trefzer, Uwe, MD
Davies, Michael A, MD
Kefford, Richard F, Prof
Ascierto, Paolo A, MD
Chapman, Paul B, MD
Puzanov, Igor, MD
Hauschild, Axel, MD
Robert, Caroline, PhD
Algazi, Alain, MD
Mortier, Laurent, Prof
Tawbi, Hussein, PhD
Wilhelm, Tabea, MD
Zimmer, Lisa, MD
Switzky, Julie, MSN
Swann, Suzanne, PhD
Martin, Anne-Marie, PhD
Guckert, Mary, MSN
Goodman, Vicki, MD
Streit, Michael, MD
Kirkwood, John M, Prof
Schadendorf, Dirk, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1751227777
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751227777
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(12)70431-X
