CREB pathway links PGE2 signaling with macrophage polarization
CREB pathway links PGE2 signaling with macrophage polarization
About this item
Full title
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Obesity is thought to promote insulin resistance in part via activation of the innate immune system. Increases in proinflammatory cytokine production by M1 macrophages inhibit insulin signaling in white adipose tissue. In contrast, M2 macrophages have been found to enhance insulin sensitivity in part by reducing adipose tissue inflammation. The par...
Alternative Titles
Full title
CREB pathway links PGE2 signaling with macrophage polarization
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Record Identifier
TN_cdi_proquest_miscellaneous_1751669827
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751669827
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1519644112
