NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates
NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Hypothalamic neurons that express neuropeptide Y (NPY) and agouti-related protein (AgRP) are thought to be critical regulators of feeding behavior and body weight. To determine whether NPY/AgRP neurons are essential in mice, we targeted the human diphtheria toxin receptor to the Agrp locus, which allows temporally controlled ablation of NPY/AgRP ne...
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NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates
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TN_cdi_proquest_miscellaneous_17580894
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17580894
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1115524
