Aspirin-Exacerbated Respiratory Disease — New Prime Suspects
Aspirin-Exacerbated Respiratory Disease — New Prime Suspects
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Publisher
United States: Massachusetts Medical Society
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Language
English
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Publisher
United States: Massachusetts Medical Society
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Scope and Contents
Contents
NSAIDs that inhibit cyclooxygenase-1 can provoke severe asthma and rhinosinusitis with nasal polyps and eosinophil infiltration. Cysteinyl leukotriene generation by the leukotriene C4 synthase pathway may cause the bronchoconstriction, vascular leak, and mucous secretion.
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Clinical Implications of Basic Research
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Full title
Aspirin-Exacerbated Respiratory Disease — New Prime Suspects
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TN_cdi_proquest_miscellaneous_1762965383
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1762965383
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ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMcibr1514013