Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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By investigating trafficking of autoreactive T cells into the CSF during experimental autoimmune encephalitis, the authors find that T cells enter the CSF from the leptomeninges, and that commuting between the leptomeninges and the CSF is regulated by integrin adhesive forces triggered by T-cell activation and/or chemokines.
T cell exchange betw...
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Full title
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
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TN_cdi_proquest_miscellaneous_1767069432
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1767069432
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature16939
