Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprin...
Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Detailed analysis of DNase-seq protocols reveals the importance of choosing the right enzyme concentration and fragment length and cautions that many transcription factor footprints may represent cutting bias.
Sequencing of DNase I hypersensitive sites (DNase-seq) is a powerful technique for identifying
cis
-regulatory elements across the...
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Full title
Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification
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TN_cdi_proquest_miscellaneous_1773828055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773828055
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.2762
