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Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773833704

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

About this item

Full title

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2016-03, Vol.19 (3), p.432-442

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The loss of nerve cells in the brain is the main event causing life-long deficits and neurological problems after stroke. Weilinger
et al
. show that NMDA receptors cause nerve cell death during stroke in an unexpected way. Although they require ligand binding and recruitment of downstream pannexin channels, NMDA receptors do not use the rece...

Alternative Titles

Full title

Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1773833704

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773833704

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.4236

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