Differential Toxicity of Antibodies to the Prion Protein: e1005401
Differential Toxicity of Antibodies to the Prion Protein: e1005401
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Publisher
San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Scope and Contents
Contents
Antibodies against the prion protein PrPC can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exhibits strong target-related toxicity, yet a subseque...
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Full title
Differential Toxicity of Antibodies to the Prion Protein: e1005401
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TN_cdi_proquest_miscellaneous_1773835042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773835042
Other Identifiers
ISSN
1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005401
