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The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the ex...

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the ex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773838119

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

About this item

Full title

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2015-05, Vol.16 (5), p.505-516

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Ezh2 is a protein methylase that epigenetically modifies chromatin. Su and colleagues identify a cytoplasmic role for Ezh2 whereby it controls the extravasation of innate leukocytes through methylation of talin and thereby influences inflammatory responses
in vivo.
A cytosolic role for the histone methyltransferase Ezh2 in regulating lymphocy...

Alternative Titles

Full title

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1773838119

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773838119

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3125

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