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Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773900684

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

About this item

Full title

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (49), p.15148-15153

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Aberrant transcription of the pericentromeric human satellite II (HSATII) repeat is present in a wide variety of epithelial cancers. In deriving experimental systems to study its deregulation, we observed that HSATII expression is induced in colon cancer cells cultured as xenografts or under nonadherent conditions in vitro, but it is rapidly lost i...

Alternative Titles

Full title

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1773900684

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773900684

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1518008112

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