Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer
Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Aberrant transcription of the pericentromeric human satellite II (HSATII) repeat is present in a wide variety of epithelial cancers. In deriving experimental systems to study its deregulation, we observed that HSATII expression is induced in colon cancer cells cultured as xenografts or under nonadherent conditions in vitro, but it is rapidly lost i...
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Full title
Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer
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TN_cdi_proquest_miscellaneous_1773900684
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773900684
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1518008112