The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis
The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Morphogenesis and remodeling of bone involve synthesis of bone matrix by osteoblasts and coordinate resorption of bone by osteoclasts. Defective bone remodeling caused by altered osteoclast activity underlies a multitude of osteopenic disorders. Receptor activator of NF-κB (RANK) and its ligand RANKL have been identified as essential factors involv...
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Full title
The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis
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TN_cdi_proquest_miscellaneous_17840004
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17840004
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1203
