Role for anti-PD-L1 immune checkpoint inhibitor in advanced urothelial carcinoma
Role for anti-PD-L1 immune checkpoint inhibitor in advanced urothelial carcinoma
About this item
Full title
Author / Creator
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Programmed death ligand 1 (PD-L1) expressed on the tumour cell surface, or on neighbouring host immune cells in the tumour microenvironment, engages the programmed death 1 (PD-1) receptor on activated cytotoxic T cells and thus downregulates the tumour-directed host immune response. Dismantling of this negative feedback loop is at the core of novel...
Alternative Titles
Full title
Role for anti-PD-L1 immune checkpoint inhibitor in advanced urothelial carcinoma
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1790459140
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1790459140
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(16)00654-1
