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Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted g...

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted g...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803085149

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

About this item

Full title

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (40), p.14512-14517

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Imprinted genes are normally selectively expressed, depending on the parent from whom the gene is inherited. These genes play important roles in control of growth and metabolism. We find that the loss of insulin and insulin-like growth factor 1 (IGF1) receptors in cells induces a major decrease in expression of multiple imprinted genes...

Alternative Titles

Full title

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803085149

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803085149

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1415475111

How to access this item