Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted g...
Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Significance Imprinted genes are normally selectively expressed, depending on the parent from whom the gene is inherited. These genes play important roles in control of growth and metabolism. We find that the loss of insulin and insulin-like growth factor 1 (IGF1) receptors in cells induces a major decrease in expression of multiple imprinted genes...
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Full title
Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes
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Record Identifier
TN_cdi_proquest_miscellaneous_1803085149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803085149
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1415475111