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GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol

GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803108344

GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol

About this item

Full title

GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (22), p.7091-7096

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance G protein-gated inwardly rectifying potassium (GIRK) channels regulate neuronal excitability and can be activated by ethanol. The role of GIRK channels in the behavioral effects of ethanol is poorly understood, however. This study shows that genetic ablation of GIRK3, one of four GIRK subunits, prevents ethanol from activating the meso...

Alternative Titles

Full title

GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803108344

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803108344

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1416146112

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