GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol
GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Significance G protein-gated inwardly rectifying potassium (GIRK) channels regulate neuronal excitability and can be activated by ethanol. The role of GIRK channels in the behavioral effects of ethanol is poorly understood, however. This study shows that genetic ablation of GIRK3, one of four GIRK subunits, prevents ethanol from activating the meso...
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Full title
GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol
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TN_cdi_proquest_miscellaneous_1803108344
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803108344
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1416146112