Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Glioblastoma (GB) is the most common and aggressive primary brain malignancy, with poor prognosis and a lack of effective therapeutic options. Accumulating evidence suggests that intratumor heterogeneity likely is the key to understanding treatment failure. However, the extent of intratumor heterogeneity as a result of tumor evolution is still poor...
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Full title
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
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TN_cdi_proquest_miscellaneous_1803119485
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803119485
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1219747110
