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microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhib...

microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhib...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803133255

microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

About this item

Full title

microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (6), p.2247-2252

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Given the trillions of microbes that inhabit the mammalian intestines, the host immune system must constantly maintain a balance between tolerance to commensals and immunity against pathogens to avoid unnecessary immune responses against otherwise harmless bacteria. Misregulated responses can lead to inflammatory bowel diseases such as ulcerative c...

Alternative Titles

Full title

microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803133255

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803133255

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1322269111

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