Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium chann...
Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Significance Voltage-gated sodium (Na ᵥ) channels control neuronal signaling and are key targets for local anesthetics, antiepileptics, and therapeutics for a range of disorders. Multimicrosecond Anton simulations have provided completely unbiased molecular-level views of the interactions of lipophilic drugs with the recently solved bacterial chann...
Alternative Titles
Full title
Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1803134601
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803134601
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1408710111
