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Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory corte...

Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory corte...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803158562

Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis

About this item

Full title

Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis

Publisher

Washington, DC: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (25), p.10306-10311

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences

More information

Scope and Contents

Contents

Sensory abnormalities such as numbness and paresthesias are often the earliest symptoms in neuroinflammatory diseases including multiple sclerosis. The increased production of various cytokines occurs in the early stages of neuroinflammation and could have detrimental effects on the central nervous system, thereby contributing to sensory and cognit...

Alternative Titles

Full title

Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803158562

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803158562

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1222895110

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