High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-emb...
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue
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Author / Creator
Ly, Alice , Buck, Achim , Balluff, Benjamin , Sun, Na , Gorzolka, Karin , Feuchtinger, Annette , Janssen, Klaus-Peter , Kuppen, Peter J K , van de Velde, Cornelis J H , Weirich, Gregor , Erlmeier, Franziska , Langer, Rupert , Aubele, Michaela , Zitzelsberger, Horst , McDonnell, Liam , Aichler, Michaela and Walch, Axel
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Formalin-fixed paraffin embedding (FFPE) of tissues has been assumed to alter the metabolite content or chemical state, hampering metabolomics studies. Here, Ly
et al
. describe reproducible metabolomic analysis of FFPE samples by mass spectrometry imaging.
Formalin-fixed and paraffin-embedded (FFPE) tissue specimens are the gold standard...
Alternative Titles
Full title
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue
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Record Identifier
TN_cdi_proquest_miscellaneous_1804863289
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1804863289
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/nprot.2016.081