Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice
Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Reconstitution of female germ cell development in vitro is a key challenge in reproductive biology and medicine. We show here that female (XX) embryonic stem cells and induced pluripotent stem cells in mice are induced into primordial germ cell-like cells (PGCLCs), which, when aggregated with female gonadal somatic cells as reconstituted ovaries, u...
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Full title
Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice
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TN_cdi_proquest_miscellaneous_1808087854
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808087854
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1226889
