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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse mode...

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse mode...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808124930

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

About this item

Full title

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Publisher

United States

Journal title

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Cramer et al. (Reports, 23 March 2012, p. 1503; published online 9 February 2012) reported that bexarotene rapidly reduces β-amyloid (Aβ) levels and plaque burden in two mouse models of Aβ deposition in Alzheimer's disease (AD). We now report that, although bexarotene reduces soluble Aβ40 levels in one of the mouse models, the drug has no impact on...

Alternative Titles

Full title

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1808124930

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808124930

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1235505

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