Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain
Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
Neural circuits are shaped by elimination of early-formed redundant synapses during postnatal development. Retrograde signaling from postsynaptic cells regulates synapse elimination. In this work, we identified semaphorins, a family of versatile cell recognition molecules, as retrograde signals for elimination of redundant climbing fiber to Purkinj...
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Full title
Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain
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TN_cdi_proquest_miscellaneous_1808125899
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808125899
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1252514
