Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective
Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective
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Cherepanova, Olga A , Gomez, Delphine , Shankman, Laura S , Swiatlowska, Pamela , Williams, Jason , Sarmento, Olga F , Alencar, Gabriel F , Hess, Daniel L , Bevard, Melissa H , Greene, Elizabeth S , Murgai, Meera , Turner, Stephen D , Geng, Yong-Jian , Bekiranov, Stefan , Connelly, Jessica J , Tomilin, Alexey and Owens, Gary K
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The pluripotency factor OCT4 is expressed in smooth muscle cells of atherosclerotic lesions in both mice and humans, and has atheroprotective effects in mice.
Although somatic cell activation of the embryonic stem cell (ESC) pluripotency factor OCT4 has been reported, this previous work has been controversial and has not demonstrated a functiona...
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Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective
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TN_cdi_proquest_miscellaneous_1808610114
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808610114
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4109
