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PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival...

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808630731

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

About this item

Full title

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2016-07, Vol.18 (7), p.803-813

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tumours exist in a hypoxic microenvironment and must limit excessive oxygen consumption. Hypoxia-inducible factor (HIF) controls mitochondrial oxygen consumption, but how/if tumours regulate non-mitochondrial oxygen consumption (NMOC) is unknown. Protein-tyrosine phosphatase-1B (PTP1B) is required for
Her2/Neu
-driven breast cancer (BC) in mi...

Alternative Titles

Full title

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1808630731

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808630731

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3376

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