PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival...
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
About this item
Full title
Author / Creator
Banh, Robert S. , Iorio, Caterina , Marcotte, Richard , Xu, Yang , Cojocari, Dan , Rahman, Anas Abdel , Pawling, Judy , Zhang, Wei , Sinha, Ankit , Rose, Christopher M. , Isasa, Marta , Zhang, Shuang , Wu, Ronald , Virtanen, Carl , Hitomi, Toshiaki , Habu, Toshiyuki , Sidhu, Sachdev S. , Koizumi, Akio , Wilkins, Sarah E. , Kislinger, Thomas , Gygi, Steven P. , Schofield, Christopher J. , Dennis, James W. , Wouters, Bradly G. and Neel, Benjamin G.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Tumours exist in a hypoxic microenvironment and must limit excessive oxygen consumption. Hypoxia-inducible factor (HIF) controls mitochondrial oxygen consumption, but how/if tumours regulate non-mitochondrial oxygen consumption (NMOC) is unknown. Protein-tyrosine phosphatase-1B (PTP1B) is required for
Her2/Neu
-driven breast cancer (BC) in mi...
Alternative Titles
Full title
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
Authors, Artists and Contributors
Author / Creator
Iorio, Caterina
Marcotte, Richard
Xu, Yang
Cojocari, Dan
Rahman, Anas Abdel
Pawling, Judy
Zhang, Wei
Sinha, Ankit
Rose, Christopher M.
Isasa, Marta
Zhang, Shuang
Wu, Ronald
Virtanen, Carl
Hitomi, Toshiaki
Habu, Toshiyuki
Sidhu, Sachdev S.
Koizumi, Akio
Wilkins, Sarah E.
Kislinger, Thomas
Gygi, Steven P.
Schofield, Christopher J.
Dennis, James W.
Wouters, Bradly G.
Neel, Benjamin G.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1808630731
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808630731
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3376