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A2.10SLE associated UBE2L3 haplotype modulates plasma cell differentiation via genotypic regulation...

A2.10SLE associated UBE2L3 haplotype modulates plasma cell differentiation via genotypic regulation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808637743

A2.10SLE associated UBE2L3 haplotype modulates plasma cell differentiation via genotypic regulation of NF- Kappa B

About this item

Full title

A2.10SLE associated UBE2L3 haplotype modulates plasma cell differentiation via genotypic regulation of NF- Kappa B

Journal title

Annals of the rheumatic diseases, 2015-03, Vol.74 (Suppl 1), p.A19-A20

Language

English

Formats

More information

Scope and Contents

Contents

Background and objectivesGenome-wide association studies have identified a strong association between a single risk haplotype of the UBE2L3 gene and systemic lupus erythematosus (SLE). UBE2L3 is an E2 ubiquitin-conjugating enzyme that critically regulates ubiquitination by the linear ubiquitin chain assembly complex (LUBAC) with consequent effects...

Alternative Titles

Full title

A2.10SLE associated UBE2L3 haplotype modulates plasma cell differentiation via genotypic regulation of NF- Kappa B

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1808637743

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808637743

Other Identifiers

ISSN

0003-4967

DOI

10.1136/annrheumdis-2015-207259.45

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