Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Jian Yang and colleagues propose a method that integrates summary data from GWAS and eQTL studies to identify genes whose expression levels are associated with complex traits because of pleiotropy. They apply the method to five human complex traits and prioritize 126 genes for future functional studies.
Genome-wide association studies (GWAS) hav...
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Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
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TN_cdi_proquest_miscellaneous_1808741499
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808741499
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3538
