Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positi...
Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer
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Publisher
England: Oxford University Press
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Language
English
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Publisher
England: Oxford University Press
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Scope and Contents
Contents
Activating mutations in the estrogen receptor 1 (ESR1) gene are acquired on treatment and can drive resistance to endocrine therapy. Because of the spatial and temporal limitations of needle core biopsies, our goal was to develop a highly sensitive, less invasive method of detecting activating ESR1 mutations via circulating cell-free DNA (cfDNA) an...
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Full title
Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer
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Record Identifier
TN_cdi_proquest_miscellaneous_1811908016
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1811908016
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ISSN
0009-9147
E-ISSN
1530-8561
DOI
10.1373/clinchem.2015.238717