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Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positi...

Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1811908016

Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer

About this item

Full title

Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer

Publisher

England: Oxford University Press

Journal title

Clinical chemistry (Baltimore, Md.), 2015-07, Vol.61 (7), p.974-982

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Activating mutations in the estrogen receptor 1 (ESR1) gene are acquired on treatment and can drive resistance to endocrine therapy. Because of the spatial and temporal limitations of needle core biopsies, our goal was to develop a highly sensitive, less invasive method of detecting activating ESR1 mutations via circulating cell-free DNA (cfDNA) an...

Alternative Titles

Full title

Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1811908016

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1811908016

Other Identifiers

ISSN

0009-9147

E-ISSN

1530-8561

DOI

10.1373/clinchem.2015.238717

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