The Anti-HIV Pentameric Pseudopeptide HB-19 is Preferentially Taken up in vivo by Lymphoid Organs Wh...
The Anti-HIV Pentameric Pseudopeptide HB-19 is Preferentially Taken up in vivo by Lymphoid Organs Where It Forms a Complex with Nucleolin
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The HB-19 pseudopeptide 5[Kψ(CH2N)PR]-TASP, ψ(CH2N) for reduced peptide bond, is a specific inhibitor of HIV infection in different CD4+cell lines and in primary T-lymphocytes and macrophages. It blocks virus-particle attachment to permissive cells by binding and forming a stable complex with nucleolin expressed on the cell surface. Here, we have i...
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Full title
The Anti-HIV Pentameric Pseudopeptide HB-19 is Preferentially Taken up in vivo by Lymphoid Organs Where It Forms a Complex with Nucleolin
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TN_cdi_proquest_miscellaneous_18130874
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18130874
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.221467298
