The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6
The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6
About this item
Full title
Author / Creator
Küffer, Alexander , Lakkaraju, Asvin K. K. , Mogha, Amit , Petersen, Sarah C. , Airich, Kristina , Doucerain, Cédric , Marpakwar, Rajlakshmi , Bakirci, Pamela , Senatore, Assunta , Monnard, Arnaud , Schiavi, Carmen , Nuvolone, Mario , Grosshans, Bianka , Hornemann, Simone , Bassilana, Frederic , Monk, Kelly R. and Aguzzi, Adriano
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The cellular prion protein PrP
C
promotes peripheral myelin homeostasis by acting on a G protein-coupled receptor to increase levels of cyclic AMP in Schwann cells.
What does prion protein do?
The cellular prion protein PrP
C
is known chiefly in the context of prion diseases. The prion gene
Prnp
was cloned in 1985, and
Pr...
Alternative Titles
Full title
The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1815371371
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1815371371
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19312
