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Tight junctions: from simple barriers to multifunctional molecular gates

Tight junctions: from simple barriers to multifunctional molecular gates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1815690295

Tight junctions: from simple barriers to multifunctional molecular gates

About this item

Full title

Tight junctions: from simple barriers to multifunctional molecular gates

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2016-09, Vol.17 (9), p.564-580

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Tight junctions are intercellular adhesion complexes in epithelia and endothelia that control paracellular permeability. This paracellular diffusion barrier is semipermeable: it is size- and charge-selective.
Paracellular ion permeability at tight junctions is largely determined by their claudin composition. Claudins are a family o...

Alternative Titles

Full title

Tight junctions: from simple barriers to multifunctional molecular gates

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1815690295

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1815690295

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/nrm.2016.80

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