Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities
Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities
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Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Summary Research advances support the idea that excessive activation of the glutamatergic pathway plays an important part in the pathophysiology of multiple sclerosis. Beyond the well established direct toxic effects on neurons, additional sites of glutamate-induced cell damage have been described, including effects in oligodendrocytes, astrocytes,...
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Full title
Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities
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TN_cdi_proquest_miscellaneous_1815692663
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1815692663
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ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(16)30165-X
