Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrP(Sc) Accumulation In Vitro an...
Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrP(Sc) Accumulation In Vitro and Prion Infectivity In Vivo
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Wang, Jing , Zhang, Bao-Yun , Zhang, Jin , Xiao, Kang , Chen, Li-Na , Wang, Hui , Sun, Jing , Shi, Qi and Dong, Xiao-Ping
Publisher
United States
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English
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United States
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Prion diseases are transmissible and invariably fatal neurodegenerative disorders, which still lack of efficacious prophylactic and therapeutic tools. Our previous study has proposed that the natural phytoalexin, resveratrol, can reduce the amounts of PrP(Sc) in a scrapie-infected cell line SMB-S15. To address its anti-prion efficacy, the inhibitiv...
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Full title
Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrP(Sc) Accumulation In Vitro and Prion Infectivity In Vivo
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TN_cdi_proquest_miscellaneous_1817853115
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1817853115
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E-ISSN
1559-1182
DOI
10.1007/s12035-015-9464-z