Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization
Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization
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Publisher
England: Oxford University Press
Journal title
Language
English
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Publication information
Publisher
England: Oxford University Press
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Scope and Contents
Contents
Precision medicine is dependent on identifying actionable mutations in tumors. Accurate detection of mutations is often problematic in formalin-fixed paraffin-embedded (FFPE) tissues. DNA extracted from formalin-fixed tissues is fragmented and also contains DNA lesions that are the sources of sequence artifacts. Sequence artifacts can be difficult...
Alternative Titles
Full title
Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1819141674
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1819141674
Other Identifiers
ISSN
0009-9147
E-ISSN
1530-8561
DOI
10.1373/clinchem.2014.223040
