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Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NE...

Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NE...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1825566101

Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2

About this item

Full title

Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2015-11, Vol.350 (6263), p.961-965

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Axon pathfinding is orchestrated by numerous guidance cues, including Slits and their Robo receptors, but it remains unclear how information from multiple cues is integrated or filtered. Robo3, a Robo family member, allows commissural axons to reach and cross the spinal cord midline by antagonizing Robo1/2–mediated repulsion from midline-expressed...

Alternative Titles

Full title

Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1825566101

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1825566101

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aad2615

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