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P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer

P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1826629872

P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer

About this item

Full title

P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer

Publisher

England: Taylor & Francis

Journal title

Drug development and industrial pharmacy, 2016-04, Vol.42 (4), p.668-675

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

The aim of this study was to synthesize the preactivated thiomer poly(acrylic acid)-cyteine-2-mercaptonicotinic acid (PAA-Cys-2MNA) and to evaluate its P-glycoprotein (P-gp) inhibitory properties. The thiomer (PAA-Cys) was synthesized by covalent immobilization of thiol groups on poly(acrylic acid) (PAA) with a molecular mass of 250 kDa followed by...

Alternative Titles

Full title

P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1826629872

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1826629872

Other Identifiers

ISSN

0363-9045

E-ISSN

1520-5762

DOI

10.3109/03639045.2015.1075025

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