New insights in the molecular signature of advanced medullary thyroid cancer: evidence of a bad outc...
New insights in the molecular signature of advanced medullary thyroid cancer: evidence of a bad outcome of cases with double RET mutations
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England: BMJ Publishing Group LTD
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Language
English
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Publisher
England: BMJ Publishing Group LTD
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BackgroundThe RET proto-oncogene is responsible for the pathogenesis of hereditary (98%) and sporadic (40%) medullary thyroid carcinoma (MTC). In sporadic MTC, somatic RET mutations are associated with a poor prognosis.ObjectivesWe looked at the genetic profile of patients with advanced and metastatic MTC. The correlation between these mutations an...
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New insights in the molecular signature of advanced medullary thyroid cancer: evidence of a bad outcome of cases with double RET mutations
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TN_cdi_proquest_miscellaneous_1826737633
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1826737633
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ISSN
0022-2593
E-ISSN
1468-6244
DOI
10.1136/jmedgenet-2016-103833
