Twenty years on: the impact of fragments on drug discovery
Twenty years on: the impact of fragments on drug discovery
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Fragment-based drug discovery (FBDD) is playing an increasingly important part in delivering candidates to the clinic.
Compared with screens of lead- or drug-sized molecules, fragments allow for a more thorough search of chemical space and can lead to superior molecules.
Fragments can provide fundamental insights into molecular...
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Twenty years on: the impact of fragments on drug discovery
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TN_cdi_proquest_miscellaneous_1827894194
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827894194
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd.2016.109
