DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications
DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications
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England: Oxford University Press
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English
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England: Oxford University Press
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It is documented that in tumor cell lines, the hTERT gene exhibits prominent methylation at a CpG island rich region about -600 bp upstream of the transcription start site, but mixed or allelically absent around ±150 bp region. Given the potential clinical implications of the findings in breast cancer diagnostics, we set out to investigate if such...
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DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications
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TN_cdi_proquest_miscellaneous_1835368545
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835368545
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ISSN
0007-5027
E-ISSN
1943-7730
DOI
10.1093/labmed/lmw043