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DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications

DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835368545

DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications

About this item

Full title

DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications

Publisher

England: Oxford University Press

Journal title

Laboratory medicine, 2016-11, Vol.47 (4), p.293-299

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

It is documented that in tumor cell lines, the hTERT gene exhibits prominent methylation at a CpG island rich region about -600 bp upstream of the transcription start site, but mixed or allelically absent around ±150 bp region. Given the potential clinical implications of the findings in breast cancer diagnostics, we set out to investigate if such...

Alternative Titles

Full title

DNA Methylation of the hTERT Gene in Breast Cancer Revisited: Diagnostic and Clinical Implications

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1835368545

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835368545

Other Identifiers

ISSN

0007-5027

E-ISSN

1943-7730

DOI

10.1093/labmed/lmw043

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