Beyond pan-B-cell-directed therapy — new avenues and insights into the pathogenesis of SLE
Beyond pan-B-cell-directed therapy — new avenues and insights into the pathogenesis of SLE
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Key Points
Pan-B-cell-directed agents show only modest evidence of clinical benefit in systemic lupus erythematosus (SLE), despite the crucial role of B-lineage cells in its pathogenesis
Trials of pan-B-cell-directed agents have provided evidence of antibody-independent contributions of CD20
+
B cells as well as antibody–dependent contr...
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Full title
Beyond pan-B-cell-directed therapy — new avenues and insights into the pathogenesis of SLE
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TN_cdi_proquest_miscellaneous_1835403089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835403089
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ISSN
1759-4790
E-ISSN
1759-4804
DOI
10.1038/nrrheum.2016.158
