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The real-time quaking-induced conversion assay for detection of human prion disease and study of oth...

The real-time quaking-induced conversion assay for detection of human prion disease and study of oth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835418938

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

About this item

Full title

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2016-11, Vol.11 (11), p.2233-2242

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This 96-well-plate ‘real-time quaking-induced conversion’ assay allows the detection of abnormal prion protein in human brain and CSF samples. It can be applied to study many protein misfolding diseases, as well as for drug screening and prion strain discrimination.
The development and adaption of
in vitro
misfolded protein amplification s...

Alternative Titles

Full title

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1835418938

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835418938

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/nprot.2016.120

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