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Transition states and cell fate decisions in epigenetic landscapes

Transition states and cell fate decisions in epigenetic landscapes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837312323

Transition states and cell fate decisions in epigenetic landscapes

About this item

Full title

Transition states and cell fate decisions in epigenetic landscapes

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Genetics, 2016-11, Vol.17 (11), p.693-703

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Formal representations of Waddington's epigenetic landscape represent cell fate decisions as smooth, continuous events in which cells follow predetermined trajectories. Here, the authors provide an alternative interpretation and posit that fate decisions are discontinuous, stochastic events within cell lineages.
Waddington's epigenetic landscape...

Alternative Titles

Full title

Transition states and cell fate decisions in epigenetic landscapes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1837312323

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837312323

Other Identifiers

ISSN

1471-0056

E-ISSN

1471-0064

DOI

10.1038/nrg.2016.98

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