Transition states and cell fate decisions in epigenetic landscapes
Transition states and cell fate decisions in epigenetic landscapes
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Formal representations of Waddington's epigenetic landscape represent cell fate decisions as smooth, continuous events in which cells follow predetermined trajectories. Here, the authors provide an alternative interpretation and posit that fate decisions are discontinuous, stochastic events within cell lineages.
Waddington's epigenetic landscape...
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Full title
Transition states and cell fate decisions in epigenetic landscapes
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TN_cdi_proquest_miscellaneous_1837312323
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837312323
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ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/nrg.2016.98