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Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA bar...

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA bar...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837323537

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

About this item

Full title

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2016-10, Vol.34 (10), p.1037-1045

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Detection of more than 1,000 different T-cell specificities in parallel facilitates identification of cancer and autoimmune antigens.
Identification of the peptides recognized by individual T cells is important for understanding and treating immune-related diseases. Current cytometry-based approaches are limited to the simultaneous screening of...

Alternative Titles

Full title

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1837323537

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837323537

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.3662

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