Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with...
Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline
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Author / Creator
Liu, P-P , Liu, J , Jiang, W-Q , Carew, J S , Ogasawara, M A , Pelicano, H , Croce, C M , Estrov, Z , Xu, R-H , Keating, M J and Huang, P
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western countries and is currently incurable due, in part, to difficulty in eliminating the leukemia cells protected by stromal microenvironment. Based on previous observations that CLL cells exhibit mitochondrial dysfunction and altered lipid metabolism and that carnitine...
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Full title
Elimination of chronic lymphocytic leukemia cells in stromal microenvironment by targeting CPT with an antiangina drug perhexiline
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TN_cdi_proquest_miscellaneous_1837339679
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837339679
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2016.103