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The pathway to GTPase activation of elongation factor SelB on the ribosome

The pathway to GTPase activation of elongation factor SelB on the ribosome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1839738669

The pathway to GTPase activation of elongation factor SelB on the ribosome

About this item

Full title

The pathway to GTPase activation of elongation factor SelB on the ribosome

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2016-12, Vol.540 (7631), p.80-85

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

In all domains of life, selenocysteine (Sec) is delivered to the ribosome by selenocysteine-specific tRNA (tRNA
Sec
) with the help of a specialized translation factor, SelB in bacteria. Sec-tRNA
Sec
recodes a UGA stop codon next to a downstream mRNA stem–loop. Here we present the structures of six intermediates on the pathway of UGA re...

Alternative Titles

Full title

The pathway to GTPase activation of elongation factor SelB on the ribosome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1839738669

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1839738669

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature20560

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