Chromosome Translocations and Covert Leukemic Clones are Generated during Normal Fetal Development
Chromosome Translocations and Covert Leukemic Clones are Generated during Normal Fetal Development
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Studies on monozygotic twins with concordant leukemia and retrospective scrutiny of neonatal blood spots of patients with leukemia indicate that chromosomal translocations characteristic of pediatric leukemia often arise prenatally, probably as initiating events. The modest concordance rate for leukemia in identical twins (≈5%), protracted latency,...
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Full title
Chromosome Translocations and Covert Leukemic Clones are Generated during Normal Fetal Development
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TN_cdi_proquest_miscellaneous_18413522
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18413522
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.112218799
