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Plasma membrane proteomics identifies Notch1 as a potential regulator of ras-induced senescence

Plasma membrane proteomics identifies Notch1 as a potential regulator of ras-induced senescence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846403102

Plasma membrane proteomics identifies Notch1 as a potential regulator of ras-induced senescence

About this item

Full title

Plasma membrane proteomics identifies Notch1 as a potential regulator of ras-induced senescence

Publisher

London: Elsevier Ltd

Journal title

The Lancet (British edition), 2013-02, Vol.381, p.S49-S49

Language

English

Formats

Publication information

Publisher

London: Elsevier Ltd

More information

Scope and Contents

Contents

Abstract Background Oncogene-induced senescence (OIS) is an intrinsic tumour suppressor mechanism leading to stable cell-cycle arrest in response to oncogene activation. OIS is a heterogeneous phenotype of multiple effector mechanisms; understanding of in-vivo OIS is lacking because of the difficulty in identifying senescence. We wished to establis...

Alternative Titles

Full title

Plasma membrane proteomics identifies Notch1 as a potential regulator of ras-induced senescence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1846403102

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846403102

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(13)60489-4

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