Dynamic Scenario of Membrane Binding Process of Kalata B1: e114473
Dynamic Scenario of Membrane Binding Process of Kalata B1: e114473
About this item
Full title
Dynamic Scenario of Membrane Binding Process of Kalata B1: e114473
Author / Creator
Journal title
PloS one, 2014-12, Vol.9 (12)
Language
English
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Scope and Contents
Contents
Kalata B1 (kB1), a cyclotide that has been used in medical applications, displays cytotoxicity related to membrane binding and oligomerization. Our molecular dynamics simulation results demonstrate that Trp19 in loop 5 of both monomeric and tetrameric kB1 is a key residue for initial anchoring in the membrane binding process. This residue also faci...
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Full title
Dynamic Scenario of Membrane Binding Process of Kalata B1: e114473
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1846421850
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846421850
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0114473
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